It is not necessary to uninstall MS Office if you have the 32-bit office installed. This documentation link describes how to install both the 32-bit and 64-bit database engines as needed. Sometimes a computer gets 'confused' and installing or re-installing this database engine will get everything working again.

If a repair of Office does not help, you probably need to install the 64-bit Microsoft Access Database Engine. You must have Microsoft(R) Excel installed on your machine It may be because you are using a 32-bit version of Office, or sometimes Office needs to be repaired (even though everything else seems to be working fine.) Check out this Knowledge Base Article: Solution Details Issues can arise when 64-bit programs like Altium versions 18 and newer try to access data if the operating system does not utilize a 64-bit engine for this task. For more information and application solutions, click here.' Starting in Version: 18.0 Altium Designer requires that the 64-bit Microsoft Access Database Engine be installed. 'An error occurred while establishing a connection to the database. 'The operating system is not presently configured to run this application.' as described in this forum post. This article should help you out if you get the message: This article covers how to use Database Libraries with 32-bit and 64-bit Altium Designer Software on the same computer and how to use a 64-bit version of Altium Designer when you are using a 32-bit version of Office.

Altium Designer 23.8.1.32 downloading